Novel drug for Alzheimer's Disease?

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>> Saturday, January 28, 2012

Researchers have reported the novel compound with neurotrophic activity for cognitive enhancement and alzheimer's disease (AD). They previously found pyrazole derivative of curcumin called CNB001 (structure 1) with broad neuroprotective effects (J. Neurochem, 2008, 105, 1336). Due to the presence of hydroxyl groups in aromatic ring, the compound was believed to be modified by sulfation and carbohydrate addition in vivo which limits the brain penetration.

Happy new year 2012 and popular posts of 2011

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>> Monday, January 02, 2012

I wish all medchemblog readers a very very happy and healthy new year 2012. I hope this year brings a lot of success in your life. In this post I would like to take an opportunity to share the top 10 posts and the top 10 countries to visit the medchemblog in 2011.

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